CORDIS Project
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This project focuses on understanding dendritic cells, a type of immune cell, by studying a specific marker. It aims to develop better models for characterizing these cells in both mice and humans, which could enhance cancer immunotherapy strategies.
The dendritic cell (DC) system of antigen-presenting cells controls immunity and tolerance.
The unresolved issues on DC heterogeneity represent an important hurdle in the development of DC-based immunotherapies.
The identification of the DNGR-1 marker by the host lab allows us to develop better models for characterising human and mouse DC.
In the mouse, this marker is selectively expressed in mouse CD8+DC and then, we believe that it constitutes a better marker for CD8+DC in vivo and, therefore,…
CANCER RESEARCH UK LBG
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