CORDIS Project
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This project studies the role of the FtsK protein in bacterial cell division, particularly its function in DNA transfer during septation in Escherichia coli. It aims to uncover the mechanisms that ensure proper chromosome segregation and cell division in bacteria.
The molecular mechanisms that serve to couple DNA replication, chromosome segregation and cell division are largely unknown in bacteria.
This led a considerable interest to the study of Escherichia coli FtsK, an essential cell division protein that assembles into DNA-pumps to transfer chromosomal DNA between the two daughter cell compartments during septation.
Indeed, our recent work suggests that FtsK might regulate the late stages of septation to ensure DNA is fully cleared from the septum bef…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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