CORDIS Project
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This project focuses on developing DNA-based molecular computers for diagnosing diseases by monitoring microRNA levels. The technology aims to simplify the detection and classification of these biomarkers, making it suitable for point-of-care applications.
Changes in human microRNA (miRNA) levels are associated with several important human diseases.
Monitoring changes in miRNA levels would enable clinicians to perform diagnosis and evaluate therapeutic efficacy of drugs.
In principle, changes in a miRNA signature could be detected by existing methods such as quantitative reverse transcription PCR (RT-qPCR).
However, the experimental complexity and computational analysis of the data prevents the measurements of miRNA signatures in a clinical settin…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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