CORDIS Project
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This project explores DNA repair mechanisms, particularly homologous recombination, to understand how cells maintain genetic stability and diversity. It aims to develop new biochemical methods to study these processes in living cells.
For cells and organisms to survive and propagate, they must accurately pass on their genetic information to the next generation.
Errors in this process may arise from spontaneous mistakes in normal cellular metabolism, or from exposure to external agents, such as chemical mutagens and radiation.
To protect themselves from the consequences of DNA damage, cells have evolved a vast array of pathways DNA repair mechanisms, each optimised for the resolution of a particular problem.
One method of DNA…
THE UNIVERSITY OF SUSSEX
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