CORDIS Project
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This project investigates how transcription factors regulate gene expression by mapping their binding to DNA in various cell types. It employs high-throughput techniques to explore the dynamics of transcription factor networks, aiming to enhance understanding of cellular differentiation and responses to stimuli.
Transcription factors (TF) regulate genome function by controlling gene expression.
Comprehensive characterization of the in vivo binding of TF to the DNA in relevant primary models is a critical step towards a global understanding of the human genome.
Recent advances in high-throughput genomic technologies provide an extraordinary opportunity to develop and apply systematic approaches to learn the underline principles and mechanisms of mammalian transcriptional networks.
The premise of this pro…
WEIZMANN INSTITUTE OF SCIENCE
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