CORDIS Project
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This project investigates the role of specific microRNAs in regulating melanoma invasiveness. By understanding the molecular mechanisms involved, it aims to identify new therapeutic strategies for treating this aggressive form of skin cancer.
Melanoma, a melanocytic neoplasm, is a highly lethal and treatment-refractory cancer.
While progress has been made in deciphering the molecular underpinnings of melanoma, successful treatment for metastatic melanoma remains frustratingly uncommon.
Complex phenotypes such as changes in cell morphology, motility, and invasiveness are rarely regulated by a single gene.
Because a single microRNA (miR) may target thousands of genes, it is possible that altered expression of a single miR can regulate…
TEL AVIV UNIVERSITY
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