CORDIS Project
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This research explores the neural mechanisms of movement initiation, distinguishing between self-paced and externally cued actions. By studying the motor thalamus and its connections, the project aims to enhance understanding of movement disorders like Parkinson's disease and the effects of external cues on motor contr…
The initiation of movement, whether triggered by an internal (self-paced) or external stimulus (cued), relies on complex neural circuitry involving the pre-motor and motor cortex, basal ganglia, cerebellum, midbrain, and thalamus.
The motor thalamus (mThal) integrates inputs from these structures to orchestrate the shift of cortical activity from a preparatory into an execution mode, resulting in action initiation.
However, it is unclear whether the activity in the mThal that releases the motor…
FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD
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