CORDIS Project
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This project investigates the role of collagen type I degradation in fibrosis-related chronic diseases. By exploring molecular mechanisms and employing advanced research techniques, it aims to enhance understanding and develop new therapeutic strategies for managing fibrosis.
Fibrosis-related chronic diseases (CDs) are amongst the biggest societal burdens in Europe, with fibrosis being recognised as the main driver of morbidity and mortality.
Extracellular matrix (ECM) is a key player in fibrosis, with an excessive accumulation of type I collagen (COL1) being a predominant component of the fibrotic tissue.
While the increase in COL1 production is considered a main driver of fibrosis, respective drugs had limited efficacy.
New evidence indicates that attenuation of CO…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Denmark, Herlev
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
France, Montpellier
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
BIOMEDICAL RESEARCH FOUNDATION, ACADEMY OF ATHENS
Greece, Athina
Type: Research institute
Activity type: Research Organisations
SME: No
Germany, Hannover
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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