CORDIS Project
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This project aims to advance kidney disease research by developing methods to directly reprogram fibroblasts into kidney cells. This approach seeks to create patient-specific models for studying kidney diseases and potential therapies.
The global incidence of kidney disease is on the rise, but little progress has been made to develop novel therapies or preventative measures.New methods to generated renal tissue in vitro hold great promise for regenerative medicine and the prospect of organ replacement.
Most of the strategies employed differentiate induced pluripotent stem cells (iPSCs) into kidney organoids, which can be derived from patient tissue.
Direct reprogramming is an alternative approach to convert one cell type into…
UNIVERSITAT ZURICH
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