CORDIS Project
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This project focuses on improving gene delivery systems using polyplexes and lipid nanoparticles to enhance the transport of genetic material into target cells. It aims to understand the mechanisms of endosomal escape and optimize the release of nucleic acids for therapeutic applications.
Nucleic acid-based therapies are currently booming with the advent of mRNA vaccines formulation.
Hence, gene delivery systems employing polyplexes or lipid nanoparticles (LNPs) as versatile carriers have shown great promise for therapeutic applications due to the advantages in terms of tuneable properties and biocompatibility.
Key to the success of these therapies is the development of efficient and controlled delivery systems capable of transporting the genetic material into target cells, relea…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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