CORDIS Project
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The DiffusOMICS project develops a high-throughput fluorescence-based method to measure the rotational diffusion properties of proteins in living cells. This technology aims to detect protein aggregates associated with neurodegenerative diseases, enabling detailed molecular interaction mapping and enhancing drug screen…
Protein oligomers and aggregates are pillars of many cellular processes and can be associated with a number of life-threatening neurodegenerative diseases.
These processes are often context-dependent but are hard to detect in situ with available technologies.
The ideal instrument can target specific proteins of medical interest in their physiological contexts, resolve nano-distances (1-100 nm) and capture dynamics of association and dissociation (ns-ms).The DiffusOMICS project aims to fill this…
KUNGLIGA TEKNISKA HOEGSKOLAN
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