CORDIS Project
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This research focuses on the dynamics of DNA and its interactions with the cytoskeleton and nuclear environment. By studying chromosome behavior in yeast, the project aims to uncover the mechanical forces that influence chromatin organization and genome stability during cell division.
The structure and role of the DNA molecule raise fascinating questions regarding its dynamics, i.e. not only the tri-dimensional reorganisation associated with functional events at short time-scale, but also the structural changes, i.e. rearrangements, that occur in the chromosome over generations.
It is increasingly obvious that the physical properties of both the chromosomes and their environment the nucleoplasm, the nuclear periphery, cytoskeleton, etc. are playing important roles in the…
INSTITUT PASTEUR
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