CORDIS Project
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This research explores the role of inhibitory neurons in the mammalian neocortex and how their distribution affects the functional specialization of cortical areas. It aims to understand the developmental mechanisms that shape these circuits and their implications for brain function.
The mammalian neocortex consists of discrete, but highly interconnected, functional areas that collectively encode features of the environment, form associations between stimuli and drive behaviour by transforming sensory input into motor output.
All neocortical areas are organised into six layers containing two major classes of neurons, excitatory glutamatergic pyramidal cells and inhibitory GABAergic interneurons.
However, each area has distinctive cytoarchitectonical features and inputs that…
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