CORDIS Project
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The IMMCEPTION 2 project focuses on developing a selective antagonist for the GPCRX receptor to treat asthma. By utilizing a new transgenic mouse model, the project aims to block this receptor, potentially leading to improved management of asthma symptoms in patients.
Asthma affects approximately 3% of the population and results in 1,000 daily deaths.
It is characterized by chronic lung inflammation and airway hyperresponsiveness.
First lines of treatment have not evolved in the last decades and actual developments are essentially focusing on severe asthma management (7% of patients) via the targeting of inflammatory mediators.
Unfortunately, 60% of asthmatics still suffer from uncontrolled symptoms.The lungs are innervated by peripheral neurons expressing sp…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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