CORDIS Project
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This project investigates membrane nanotubes that connect various cell types, particularly in the immune system. It aims to understand the molecular mechanisms behind their formation and function, focusing on the proteins involved and the unique membrane composition of these structures.
Recently, membrane nanotubes have been found to connect many types of cells, including cells of the immune system.
These nanotubes contain actin filaments, are not attached to substrate, and are distinct from other cell tethers such as filopodia and membrane bridges.
Potentially, specific coupling of cells over long distances can have great significance, and evidence is mounting to suggest that membrane nanotubes may have a role, e.g., in specific cell-to-cell signalling and trafficking of patho…
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