CORDIS Project
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This project explores the mechanisms of redox signaling, which involves the reversible modification of proteins by oxidants. By investigating protein-to-protein interactions and redox relay chains, the research aims to uncover how these processes influence cellular adaptations and resilience.
Redox signaling is a process by which endogenous oxidants, derived from metabolism, reversibly modify particular thiols on particular proteins to change their functional behavior in an adaptive manner.
However, the molecular mechanisms of redox signaling remain largely unknown.
In particular, specificity and efficiency of redox signaling remain unexplained.
The now emerging solution to this conundrum is that redox signaling is mediated and channeled by protein-to-protein redox relay chains that…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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