CORDIS Project
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This project investigates the molecular mechanisms of ectopic pregnancy, where embryos implant outside the uterus. By creating a detailed transcriptome atlas and developing new computational tools, it aims to enhance understanding of trophoblast invasion and its implications for pregnancy complications.
Ectopic pregnancy affects ~2% of pregnancies and is the leading cause of death in the first trimester.
It occurs when the embryo implants outside the uterus, often in the fallopian tube.
Placentation, a critical process for pregnancy success, is severely disrupted in ectopic pregnancy.
The dysregulated trophoblast invasion in an unsuitable environment can lead to tissue rupture and life-threatening maternal bleeding.
Despite its severity, the molecular mechanisms underlying placentation and its…
GENOME RESEARCH LIMITED
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