CORDIS Project
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This project focuses on developing a computational and experimental workflow to infer regulatory networks in cells, specifically mesenchymal stem cells. It aims to model how combinations of transcription factors influence cell states, enhancing understanding of cell differentiation and providing a framework for future…
Gene regulation is one of the main drivers of a cell's fate and function, but current methods that infer genome-wide regulatory networks have problems with inferring causal and/or combinatorial interactions.
Pooled single-cell screening technologies, such as those developed in the host lab, now provide a powerful alternative to regulatory network inference.
However, as this technology matures, data analysis is now more and more becoming the rate-limiting step in inferring causal and combinatoria…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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