CORDIS Project
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This research project investigates the mechanisms of renal fibrosis in chronic kidney disease, specifically focusing on nephronophthisis, a genetic disorder. Using advanced techniques like live fluorescence microscopy and single-cell RNA sequencing, the project aims to identify disrupted signaling pathways and potentia…
Chronic kidney disease (CKD) affects up to 10% of the world population and is characterized by decreased renal filtration and scarring (fibrosis).
However, the mechanisms underlying renal fibrosis remain largely unclear, which hampers drug development.
In this research, I will elucidate mechanisms underlying renal fibrosis using state-of-the-art techniques, like live fluorescence microscopy and single-cell RNA sequencing (scRNAseq), to analyze human renal organoids. I will focus on a genetic fib…
UNIVERSITAT ZURICH
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