CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project extends the oncogenic shock model to explore how the loss of cancer dependency genes triggers cell death. It aims to develop a platform for analyzing transcriptional changes in cancer cells, which could lead to new therapeutic targets and strategies.
The oncogenic shock model has been introduced to describe the interplay between pro-survival and pro-apoptotic signals that follow an oncogene's inactivation and lead to cancer cell death.In my recent work, I demonstrated that identifying novel cancer dependencies through systematic computational analyses of CRISPR functional genetic screens and multi-omic data is an excellent means to discover and prioritise new anti-cancer therapeutic targets.
Here, I extend the oncogenic shock concept to any…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
