CORDIS Project
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This project investigates how protein circuits in cells maintain functionality despite fluctuations. It explores the roles of bifunctional enzymes and gene regulation in enhancing circuit robustness, as well as how drug combinations can influence protein dynamics, aiming to inform future medical strategies for cell con…
Cells use circuits of interacting proteins to respond to their environment.
In the past decades, molecular biology has provided detailed knowledge on the proteins in these circuits and their interactions.
To fully understand circuit function requires, in addition to molecular knowledge, new concepts that explain how multiple components work together to perform systems level functions.
Our lab has been a leader in defining such concepts, based on combined experimental and theoretical study of wel…
WEIZMANN INSTITUTE OF SCIENCE
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