CORDIS Project
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This project investigates how sensory experiences shape synaptic and circuit development in the brain during critical growth periods. It focuses on the role of a specific receptor, GluN3A, in refining synaptic connections, which is crucial for understanding neurodevelopmental disorders like autism and schizophrenia.
The postdoctoral project aims to investigate the mechanisms underlying sensory experience driven synaptic and circuit refinement that occurs during critical periods of brain development.
Presynaptic and postsynaptic refinement involving loss and strengthening of synaptic contacts are known to occur but how these processes are coordinated and remains obscure.
Failure to appropriately regulate this refinement underlies some common neurological disorders including autism and schizophrenia.
The non…
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