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The DeepRNA project investigates RNA-binding proteins associated with genetic disorders, using advanced data analysis to understand their interactions. This research aims to enhance personalized medicine by linking genetic variants to RNA-protein interactions, potentially leading to new therapeutic approaches.
RNA-binding proteins are implicated across a wide spectrum of human genetic disorders, with molecular mechanisms ranging from aggregation of proteins and RNAs to defects in splicing and translation.
Examples include heterogeneous and life-threatening genetic disorders such as Diamond-Blackfan anaemia, spinocerebellar ataxia and amyotrophic lateral sclerosis (ALS) among others.The DeepRNA project targets genetic diseases via disease-associated variants in the human transcriptome and is enabled by…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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