CORDIS Project
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This project aims to enhance deep tissue imaging in neuroscience using novel techniques like optical time reversal. By overcoming current limitations, it seeks to enable functional imaging of previously inaccessible areas of the brain, particularly in understanding neuronal circuitry.
Microscopy enabled the birth of modern neuroscience, by allowing Ramón y Cajal to formulate the neuron doctrine.
Since then, remarkable advances in optical resolution, speed and probe development allowed scientists to study the function of neuronal circuits with ever increasing detail – with one critical limitation:
No conventional microscope can focus light deeper into intact tissue than a fraction of a mm.
This leaves 90% of the intact rodent brain and over 99% of the intact primate brain inac…
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