CORDIS Project
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This project develops advanced nanopore technology for sequencing proteins. By creating synthetic nanopores that can unfold proteins and recognize amino acids, it aims to enable real-time monitoring and identification of low-abundance proteins linked to diseases.
Nanopores have emerged in the past few years as a promising analytical technique.
The basic concept of nanopore sensing is to apply a potential across individual nanoscale pores and observe the disruption of the ionic flow caused by single molecules entering the pore.
Ionic currents through protein pores have been successful at recognizing tiny differences in molecules in solution.
Most notably, arrays of thousands of nanopores integrated in low-cost and portable devices are now capable of seque…
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