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The DecOmPress project aims to understand multiple sclerosis by analyzing cellular and molecular changes in the brain. It employs single-cell genomic techniques to identify disease mechanisms and potential therapeutic targets through studies in both human and mouse models.
Multiple sclerosis (MS) is a paradigmatic progressive neuroinflammatory disease characterized by multiple lesions across the entire central nervous system including both gray and white matter areas.
Deconvoluting the spatio-temporal cellular and molecular landscape is therefore key to understanding underlying disease mechanisms and to develop cell-type specific therapies.
The DecOmPress proposal is about integrative human and mouse single-cell genomic strategies to track-down reactive cellular s…
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
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