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DECOMPACT is developing polymeric nanocapsules to deliver collagenase for treating scleroderma, a disease characterized by excessive collagen. These nanocapsules will protect the enzyme and release it upon exposure to UVA light, combining collagen degradation with anti-inflammatory effects.
“Developments of Collagenase Polymeric nanocapsules as Therapeutics (DECOMPACT)”.
The goal of this proof of concept project is the development and commercialization of a novel treatment to scleroderma.
Scleroderma is a fibrotic disease with a significant incidence in the population and is characterized by an abnormal accumulation of collagen.
Treatment of this disease involves the use of proteolytic enzymes, as collagenase, able to digest collagen fibers.
However, the labile nature of collagena…
UNIVERSIDAD COMPLUTENSE DE MADRID
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