CORDIS Project
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This project focuses on understanding how membrane proteins are produced and folded within cells. By investigating the quality control mechanisms in the endoplasmic reticulum, it aims to shed light on the processes that lead to membrane protein-related diseases.
Any cell and each of its organelles needs to interact with its environment.
Membrane proteins, which span the plasma membrane and the multiple endomembranes of a eukaryotic cell, mediate these interactions.
They allow cells to move, thrive and defend - and multicellular organisms to exist.
Humans dedicate almost one third of their genes to membrane proteins.
Failures in membrane protein biogenesis or function cause numerous human diseases from cancer to neurological disorders.By far most eukaryo…
TECHNISCHE UNIVERSITAET MUENCHEN
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