CORDIS Project
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This project investigates the molecular mechanisms behind the slow growth of Mycobacterium tuberculosis, the bacteria causing tuberculosis. By comparing it with a closely related fast-growing species, the research aims to uncover insights into the bacteria's virulence and persistence, ultimately contributing to new tre…
Tuberculosis (TB) is an infectious disease caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb), responsible for 1.5 million deaths per annum.
Moreover, due to the ability of Mtb to persist in the host, a further one third of the world population is latently infected and at risk for disease later in life.
So far, the major vaccine against TB (Bacille Calmette-Guérin vaccine) has a limited impact on the global TB epidemic, as it does not always prevent pulmonary infections in adults.…
INSTITUT PASTEUR
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