CORDIS Project
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This research focuses on understanding how peripheral regulatory T cells (pTregs) inhibit inflammation in response to harmless antigens. It aims to clarify the role of antigen-presenting cells in initiating and maintaining pTreg responses, which is crucial for developing treatments for allergies and inflammatory bowel…
Peripheral regulatory T cell (pTreg) responses are critical in inhibiting inflammation to external harmless antigens.
Studying their regulation and function is crucial for developing treatments to conditions like allergies and inflammatory bowel disease.
Antigen-presenting cells (APCs) play a pivotal role in governing tolerance: they induce pTreg, support their terminal differentiation and maintenance and are also modulated by pTreg cells in their antigen-specific tasks.
However, unclear finding…
WEIZMANN INSTITUTE OF SCIENCE
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