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The DECAF project aims to innovate carbon-carbon bond formation in organic synthesis by utilizing carboxylic esters as versatile reagents. It seeks to develop multi-catalyst reactions under visible-light irradiation to enhance the efficiency of cross-coupling reactions.
Transition-metal catalyzed cross-coupling reactions have transformed carbon-carbon bond formation in complex organic molecules, revolutionizing fields like pharmaceutical and agrochemical industries, polymers, and natural product synthesis.
Despite their vast applications, these reactions heavily rely on toxic organic halides and organometallic reagents that require multiple preparation steps and often lack stability.
Carboxylic esters (RCOOE) offer a promising alternative as they are readily av…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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