CORDIS Project
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This project investigates the relationship between cancer and aging using mouse models. It aims to identify mechanisms of aging and develop therapies for progeroid syndromes, ultimately seeking to extend human healthspan through a multidisciplinary approach.
Over many years, our research group has explored the complex relationship between cancer and ageing.
As part of this work, we have generated mouse models of protease deficiency which are protected from cancer but exhibit accelerated ageing.
Further studies with these mice have allowed us to unveil novel mechanisms of both normal and pathological ageing, to discover two new human progeroid syndromes, and to develop therapies for the Hutchinson-Gilford progeria syndrome, now in clinical trials.
We…
UNIVERSIDAD DE OVIEDO
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