CORDIS Project
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This project investigates how specific proteins, known as DEAD-box ATPases, regulate the movement and processing of RNA molecules within cells. By studying these proteins, the project aims to uncover mechanisms that control gene expression and RNA dynamics in various cellular compartments.
Life ultimately depends on the tight control of gene expression, which requires an ordered and efficient processing of various RNA molecules.
Messenger RNAs (mRNAs) bound by a constantly changing coat of passenger proteins - transit from transcription in the nucleus to translation and ultimately decay in the cytoplasm.
Similarly, ribosomal rRNAs migrate through the nucleolus where they gradually en-counter ribosomal proteins to assemble functional ribosomes.
Still, we know very little about the…
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