CORDIS Project
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This project investigates how insects detect and respond to viral infections, focusing on the role of double-stranded RNA in triggering immune responses. By identifying the receptors involved in this process, the research aims to develop strategies to control insect vectors that transmit diseases like dengue and chikun…
Important viral infectious diseases, such as dengue and chikungunya, are transmitted to humans by insectvectors.
One of the key factors that modulates whether an insect is competent or not to transmit a givenpathogen is its innate immune response.
The major antiviral defense in insects is the RNA interference(RNAi) mechanism that is activated by the detection of viral double-stranded RNA (dsRNA).
Duringantiviral RNAi a silencing immune signal is transported from one cell to another to set an ant…
INSTITUT PASTEUR
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