CORDIS Project
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The DDRAsTic project investigates the enzyme MTHFD2 to develop targeted treatments for rheumatoid arthritis. By focusing on this enzyme's role in T-cell metabolism and immune response, the project aims to create precision medicine strategies that minimize adverse effects while improving treatment efficacy for patients…
Rheumatoid arthritis (RA) is an autoimmune disease that affects millions of people worldwide, and its negative health burden is accelerating in the ageing population.
Despite many available treatments, up to 40% of RA patients do not respond sufficiently to current therapies and the needs for a precision medicine approach and new treatments are pressing.
The complexity of RA and unselective mechanisms of action of existing drugs are challenges.
Current treatments also have unintended adverse eff…
KAROLINSKA INSTITUTET
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