CORDIS Project
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This project explores the role of developmental genes in the specification of midbrain dopamine neuron subtypes and their potential misexpression in Parkinson's disease. It aims to identify these subtypes at molecular and functional levels using various models.
The goal of this project is to determine whether the expression of developmental genes in defined subpopulations of DA neurons contributes to the specification of currently unrecognized midbrain DA neuron subtypes and whether their
missexpression may contribute to the loss of DA neurons in the adulthood and to the pathogenesis of PD.Many developmental genes have been found to be implicated in the maintenance of midbrain DA neurons at postnatal and adult stages, as
assessed by the loss of DA neur…
KAROLINSKA INSTITUTET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Switzerland, Lausanne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom, Cambridge
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Spain, BARCELONA
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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