CORDIS Project
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This project focuses on understanding how certain sugars on cell surfaces facilitate viral infections. By studying the structural properties of key lectins, it aims to develop new strategies to block these interactions and prevent infections.
Multivalent lectin-sugar interactions play a key role in facilitating viral infections, affecting hundreds of millions people worldwide.
Understanding the structural mechanisms is key to be able to design glycoconjugates that can block such interactions, thereby preventing infection.
However, research advances have been hampered by inability of current methods to reveal key structural information of some important cell surface lectins.
For example, despite 17 years of extensive research, the str…
UNIVERSITY OF LEEDS
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