CORDIS Project
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The DC-PGE project focuses on developing advanced genome editing tools for human therapies. By creating enzymes that can target specific DNA sequences with high precision and safety, the project aims to improve treatment options for genetic disorders, particularly MECP2 duplication syndrome.
Genome editing in human therapies has the potential to revolutionize modern medicine.
With numerous clinical trials underway and the recent approval of the first genome editing therapy, the field is rapidly advancing.
However, there is a consensus that clinical genome editing tools must be efficient, precise and safe.
Current tools predominantly rely on host cell DNA repair pathways to complete the editing process, which poses a risk for unintended editing events.
Host cell DNA repair independen…
TECHNISCHE UNIVERSITAET DRESDEN
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