CORDIS Project
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This research develops a new model for closed-loop deep brain stimulation, aiming to improve treatment for Parkinson's disease. It focuses on simulating neural activity and creating a control strategy to enhance therapeutic effects while minimizing side effects.
Deep brain stimulation (DBS) is an effective therapy for treating the symptoms of Parkinson’s disease (PD).
Despite its success, the mechanisms of DBS are not understood and there is a need to improve DBS to improve long-term stimulation in a wider patient population, limit side-effects, and extend battery life.
Currently DBS operates in ‘open-loop’, with stimulus parameters empirically set.
Closed-loop DBS, which adjusts parameters based on the state of the system, has the potential to overcome…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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