CORDIS Project
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This project investigates how early embryonic cells decide to become either part of the placenta or the body by examining the relationship between 3D genome organization and gene expression. It utilizes advanced techniques to analyze RNA and DNA interactions in mouse embryos, aiming to identify factors that influence c…
At the onset of mammalian life, the first lineage specification decision is made where embryonic cells opt tobecome either part of the placenta or the future body.
Proper regulation of this choice is crucial for subsequentdevelopment.
However, we dont know how the transcription program and 3D genome architecture arise,interconnect, and are controlled to determine the fate of each cell in a developing embryo.
Recent studies,including my work, suggest that in addition to canonical mRNA-coding gene…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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