CORDIS Project
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This project focuses on developing new light-sensitive cancer treatment compounds that can be activated by red light in low-oxygen environments. By synthesizing ruthenium-based compounds, the goal is to enhance the effectiveness of photodynamic therapy while minimizing side effects associated with traditional chemother…
Chemotherapy is efficient in curing cancer, but most treatments are very hard to stand for the patient, and side effects limit treatment efficacy.
Phototherapy is a promising alternative, where the toxicity of a light-sensitive chemotherapeutic compound is locally released upon visible light irradiation of the compound-containing tumour.
Photodynamic therapy is already available in the clinic for oxygen-rich tumours; however, it fails when the oxygen concentration at the place of irradiation is…
UNIVERSITEIT LEIDEN
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