CORDIS Project
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This project focuses on improving chemical methods for studying proteins related to serious diseases like familial amyloid polyneuropathy. It aims to develop new ligation techniques that overcome existing limitations, enhancing the understanding of these proteins and their associated pathologies.
The area of influence of proteins comprise most biochemical reactions and recognition process that govern a living body.
However, its malfunction often lead to devastating diseases, like the ones related to Transthyretin:famylial amyloid polyneuropathy (FAP), famylial amyloid cardiomyopathy (FAC) and systemic senyl amyloidosis (SSA), cureless to date.
Chemical approaches to some of these biomacromolecules have been possible after the discovery of the native chemical ligation, which involves asse…
HUMBOLDT-UNIVERSITAET ZU BERLIN
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