CORDIS Project
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This project focuses on creating innovative X-ray contrast agents that target active proteases for improved detection of cancer and cardiovascular diseases. By enhancing imaging techniques, it aims to provide more accurate diagnoses and personalized treatment options.
The major causes of death in the Western world are cardiovascular diseases and cancer.
More accurate detection of these diseases will improve clinical outcomes.
Thus, we will develop unique X-ray contrast reagents for use in spectral computerized tomography (CT) that bind active proteases to reveal the exact location and stage of cancer and atherosclerosis.Activity-based probes (ABPs) are small molecules that covalently bind to active proteases.
Based on our success in developing optical ABPs fo…
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