CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
CSFcheck investigates the immunosuppressive nature of cerebrospinal fluid and its effects on CD8 T lymphocytes in the context of brain metastasis. The project aims to uncover mechanisms that hinder immune responses in this environment.
While the healthy brain is largely devoid of lymphoid cells, the surrounding cerebrospinal fluid (CSF) is normally populated by lymphocytes. CSF hosts an array of threatening pathologies, including leptomeningeal metastasis with unusually poor prognosis.
Despite the presence of immune cells, including CD8 T lymphocytes, this metastasis site does not respond to immunotherapy.
My preliminary data demonstrate that the molecular profile and phenotypic behavior of these CSF CD8 T cells is inconsisten…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
