CORDIS Project
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This project aims to enhance cryo-electron microscopy techniques for biological applications by integrating scanning transmission electron microscopy (STEM) with advanced imaging methods. The focus is on achieving high-resolution tomography of biological cells, improving image quality, and minimizing radiation damage d…
Cryo-electron microscopy has revolutionized the field of structural biology, primarily for macromolecular structure but also for cells and tissue sections—achieving resolutions at the limit of physical optics.
While wide-field transmission EM (TEM) with phase contrast by defocus is the most commonly used modality in biology, the alternative, scanning transmission EM (STEM), has emerged as the mode of choice for atomic resolution in materials science.
Seeking to endow biology with the benefits of…
WEIZMANN INSTITUTE OF SCIENCE
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