CORDIS Project
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This project aims to develop synthetic polymers that mimic antifreeze proteins found in polar fish, specifically targeting their ability to inhibit ice recrystallization. This technology is intended for improving cryopreservation methods for stem cells and blood cells, addressing challenges in cell storage and viabilit…
Fish living in polar oceans have evolved an elegant, macromolecular, solution to survive in sub-zero water: they secrete antifreeze (glyco)proteins (AFGPs) which have several ‘antifreeze’ effects, including ice recrystallization inhibition (IRI) - they slow the rate of ice crystal growth.
Ice crystal growth is a major problem in settings as diverse as oil fields, wind turbines, road surfaces and frozen food.
Analysis of the process of cryopreservation, whereby donor cells are frozen for later us…
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