CORDIS Project
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CryoDES is a non-toxic cryoprotectant agent designed to preserve human cells at -20ºC, replacing the toxic dimethyl sulfoxide. This innovative solution aims to enhance the safety and effectiveness of cell therapies for chronic diseases, facilitating easier storage and transportation.
Cell therapies are foreseen as the next generation therapeutics for some of the chronic diseases with highest global economic and social burden.
The market for human cell therapies has been estimated to be 8 B€ in 2021 with an expected annual growth rate of 26% until 2028.
The key aspect for the success of a cell therapy is the preservation of cells.
Currently, cells must be cryopreserved using a cryoprotectant agent (CPA) at -196ºC, in a liquid nitrogen tank.
The gold standard CPA is a chemical…
UNIVERSIDADE NOVA DE LISBOA
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