CORDIS Project
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This project aims to revolutionize the treatment of Crohn's disease and ulcerative colitis by characterizing patients based on their unique molecular pathways. It seeks to develop a personalized approach to therapy that correlates with clinical outcomes.
The clinical phenotype and the outcome of Crohn's disease (CD) and ulcerative colitis (UC), the opposite ends of chronic inflammatory bowel diseases (IBD), are heterogeneous and represent the result of a complex interplay of the gut microbiome with the immune system in genetically predisposed individuals.
Disease management is much less heterogeneous as all patients are treated using non-specific anti-inflammatory agents, and only 30-50% achieve clinical and mucosal remission -the goal of therap…
KATHOLIEKE UNIVERSITEIT LEUVEN
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