CORDIS Project
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The CrowdControl project aims to uncover how cells regulate their internal density of macromolecules, which affects their function. By using advanced imaging and genetic techniques, it seeks to identify proteins involved in density sensing and their impact on cell growth.
The cytoplasm is filled with an extremely high concentration of macromolecules that is close to the maximal physical limit.
Such a tight packing of macromolecules gives rise to a crowding effect that influences chemical reactions and protein dynamics.
Changes in crowding levels are therefore predicted to have profound consequences on cell function.
It is therefore not surprising that the overall intracellular concentration of macromolecules is very constant within a cell type, but it varies duri…
INSTITUT CURIE
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Switzerland, Zuerich
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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