CORDIS Project
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This project investigates how to enhance immune responses against tumors by targeting specific receptors on immune cells. By analyzing the structural properties of glycoprotein antigens, the research aims to improve cancer immunotherapy through better antigen presentation.
Immune therapies are therefore currently being pursued to reinvigorate the immune reaction against tumours.
This is not trivial, as the right type of immune cells must be activated against a tumour-specific antigen.
One method to achieve this is by targeting tumour antigens to certain cross-presentation-promoting receptors on antigen presenting cells.
The most intriguing of these is the mannose receptor (MR) as the method by which it does this is unknown.
This glycoprotein-binding receptor appe…
UNIVERSITEIT LEIDEN
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